Adelmidrol (1675-66-7) Soo saaraha - Cofttek

Adelmidrol (1675-66-7)

June 29, 2022

Cofttek waa soo saaraha ugu wanaagsan Adelmidrol (1675-66-7) ee Shiinaha. Warshadayadu waxay leedahay nidaam maarayn wax soo saar dhamaystiran (ISO9001 & ISO14001), oo leh awood wax soo saar bishiiba 260kg.


Status: Wax soosaarka Mass
Unugga: 1kg / bac, 25kg / Drum

Adelmidrol Smamnuucista

Name: Adelmidrol
CAS: 1675-66-7
xagiisayna 98%
Qaaciddada Molecular: C13H26N2O4
Miisaanka kelli: 274.36 g / mol
Dabaalidda: 132-134 ºC
Magaca kiimikada: N, N'-Bis (2-hydroxyethyl) nonanediamide
micne ah: Adelmidrol 1675-66-7 N,N'-bis(2-hydroxyethyl)nonanediamide AdelMitrol UNII-1BUC3685QU ka sii badan…
Furaha gudaha: PAHZPHDAJQIETD-UHFFFAOYSA-N
Kala badh: N / A
Xalka: Biyo ku milmay; Ethanol; DMSO
Xaaladda Kaydinta: 0 - 4 C muddo gaaban (maalmo illaa toddobaadyo), ama -20 C muddo dheer (bilo)
Codsiga: Waxaa si weyn loogu isticmaalaa Talyaaniga daawaynta xoolaha si loogu daweeyo caabuqa maqaarka. 2015, waxaa la ogaaday in xaruntu ay sidoo kale sameyso ficil ka hortag ah oo si nidaamsan loo siiyo 10 mg halkii kiilo ee miisaanka jirka.
Imaanshaha: budo White

 

Waa maxay Adelmidrol (1675-66-7)?

Adelmidrol waa diethanolamide semisynthetic oo ka soo jeeda azelaic acid, waxayna leedahay qaab-dhismeedka kiimikaad summaysan. Waxa loo kala saaray sidii amide, oo waxay la mid tahay palmitoylethanolamide, molecule waalidka ee fasalka ALIAmide ee daroogooyinka. ALIAmides waa koox ka mid ah derivatives acid dufan leh cannabimimetic sifooyin kuwaas oo leh ka hortagga bararka iyo saamaynta xanuunka waxaana loo maleynayaa inay ku dhaqmaan iyagoo yareynaya firfircoonida unugga mast. Adelmidrol waa anti-bararka ethanolamide oo ka soo jeeda azelaic acid.

 

Adelmidrol (1675-66-7) faa'iidooyinka

Adelmidrol waa dheesha synthetic ee azelaic acid, oo si dabiici ah u dhacda dicarboxylic acid, taas oo laga helo qaar ka mid ah miraha oo dhan iyo qadarka raadraaca ee jidhka bini'aadamka. Kiimiko ahaan, ademidrol waa N, N-bis (2-hydroxyethyl) non anediamide waana amphiphilic ama amphipathic, oo leh labadaba hydrophilic iyo hydrophobic, kuwaas oo door bidaaya ku milmay labadaba warbaahinta biyaha iyo organic. Adelmidrol waxaa iska leh qoyska aliamide, koox ka kooban asiidh dufan leh oo leh sifooyin cannabimimetic, oo awood u leh inay xakameeyaan firfircoonida unugga mast (MC) ee dhowr xaaladood oo cudur-siyeed iyo cudur. Dariiqa NF-kB ee pro-bararka ayaa si muuqata hoos loogu dhigay daawaynta adelmidrol. Saamaynta ka-hortagga bararka ee adelmidrol waxay u muuqatay inay la xiriirto firfircoonida PPAR-gamma. Adelmidrol waxay si toos ah waxtar ugu leedahay cudurrada maqaarka ee bararka bini'aadamka waxayna awoodaan inay beddelaan jawaabta bararka ee keratinocytes aadanaha. Isku darka hyaluronic acid iyo adelmidrol waxay hagaajiyaan calaamadaha osteoarthritis ee ay keento monosodium iodoacetate.

 

Adelmidrol (1675-66-7) Codsiga?

Adelmidrol waa soosaar semisynthetic ah oo ka soo jeeda azelaic acid iyo analoog ee isku dhafka anti-bararka palmitoylethanolamide (PEA), aliamide iyo xubin ka tirsan qoyska dufanka acid amide ee calaamadinta molecules leh guryaha cannabimimetic. Saamaynta anti-bararka iyo antinociceptive ee aliamides PEA iyo adelmidrol ayaa lagu soo bandhigay daraasado badan oo hore oo caafimaad, labadaba gudaha vitro iyo vivo. Ficiladooda waxaa loo maleynayaa inay sabab u tahay, ugu yaraan qayb ahaan, awooddooda ah inay wax ka beddelaan firfircoonida unugga masaska iyo sii daynta dhexdhexaadiyaha unugga mastarka ee cudurrada cudurada iyo cudurrada cudurada.

 

Adelmidrol budo for sale(Halka laga iibsado budada Adelmidrol ee bulk)

Shirkaddayadu waxay ku raaxeysataa xiriirro waqti dheer leh macaamiisheena maxaa yeelay waxaan diiradda saareynaa adeegga macaamiisha iyo bixinta alaabada waa weyn. Haddii aad xiiseyneyso badeecadeena, waxaan la qabsaneynaa qaabaynta amarrada ku habboon baahiyahaaga gaarka ah iyo waqtigeenna dhakhsaha ah ee hoggaanka amarada dammaanad-qaadista waxaad kuheli doontaa cuntadeena waqtigeeda waqtigeeda. Waxaan sidoo kale diirada saareynaa adeegyada qiimeynta ku jira. Waxaan diyaar u nahay su'aalaha adeegga iyo macluumaadka si aan u taageerno meheraddaada.

Waxaan nahay alaab-qeybiye Adelmidrol ah oo xirfadle ah dhowr sano, waxaan ku siineynaa alaab qiimo tartan leh, badeecadeena waa tayada ugu sareysa waxaana maraa baaritaan adag, madax-bannaan si loo hubiyo inay badbaado u tahay isticmaalka adduunka oo dhan.

 

tixraacyada

  1. Cerrato, Santiago; Brazil, Pilar; della Valle, Maria Federica; Miolo, Alda; Puigdemont, Anna (2012). "Saamaynta xannibaadda ee Adelmidrol ee jirka la mariyo ee antigen-ku keeno wheal maqaarka iyo habdhaqanka unugga naaska ee qaabka canine ee dermatitis". Cilmi-baarista Caafimaadka Xoolaha ee BMC. 8 (1): 230. doi: 10.1186/1746-6148-8-230. PMC 3540011. PMID 23181761.
  2. Cordaro, M; Impellizzeri, D; Gugliandolo, E; Siracusa, R; Crupi, R; Esposito, E; Cuzzocrea, S (2016). "Adelmidrol, analogue Palmitoylethanolamide, oo ah daawaynta dawooyinka cusub ee maaraynta cudurada caabuqa ee mindhicirka." Pharmacology molecular. 90 (5): 549-561. doi:10.1124/mol.116.105668. PMID 27625036.
  3. Abramo, F; Salluzzi, D; Leotta, R; Auxilia, S; Nooli, C; Miolo, A; Mantis, P; Lloyd, D. H (2008). "Mast cell morphometry iyo densitometry ee nabarrada maqaarka ee tijaabada ah oo lagu daaweeyey jel ka kooban adelmidrol: Daraasad la xakameynayo placebo". Dhaawacyada: Isku-darka Cilmi-baarista iyo Ku-dhaqanka Kiliinikada. 20 (6): 149-57. PMID 25942520.

 


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