Citicoline Sodium (33818-15-4)

Waxaa laga yaabaa 8, 2021

Cofttek waa soosaaraha ugu fiican ee Citicoline Sodium (CDP Choline Sodium) ee Shiinaha. Warshadeena waxay leedahay nidaam maareyn wax soo saar oo dhameystiran (ISO9001 & ISO14001), oo leh awood wax soo saar bille ah 220kg.

 


Status: Wax soosaarka Mass
Unugga: 1kg / bac, 25kg / Drum

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) Smamnuucista

Name: Citicoline Sodium (CDP Choline Sodium)
CAS: 33818-15-4
xagiisayna 98%
Qaaciddada Molecular: C14H25N4NaO11P2
Miisaanka kelli: 510.308 g / mol
Dhibcaha Biyaha: > 240 ° C
Magaca kiimikada: Sodium Citicoline; Cdp-choline sodium
micne ah: Sodium [[(2S,3R,4S,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]2-(trimethylazaniumyl)ethyl phosphate
Furaha gudaha: YWAFNFGRBBBDD-KDVMHAGBSA-M
Kala badh: 56 saacadood
Xalka: Dhibaatada DMSO, Biyaha (Si xoogaa)
Xaaladda Kaydinta: Qalalan, madow iyo 0 - 4 C muddo gaaban (maalmo illaa toddobaadyo) ama -20 C muddo dheer (bilo illaa sannado).
Codsiga: Citicoline Sodium waa wakiilka neerfaha iyo kaabista cuntada
Imaanshaha: White Solid White

 

Codioline Sodium (33818-15-4) Spectrum NMR

Sodium Citicoline (33818-15-4) NMR Spectrum

Haddii aad u baahan tahay COA, MSDS, HNMR qayb kasta oo badeecad ah iyo macluumaad kale ah, fadlan la soo xiriir annaga maareeyaha suuq gaynta.

 

waa maxay Citicoline Sodium (CDP Choline Sodium)(33818-15-4) ?

Budada loo yaqaan 'Citicoline Sodium' (CDP-choline Sodium, cytidine 5a-diphosphocholine) budada waa nafaqo biyo ku milma oo u adeegta sidii horudhac u ah labada choline iyo cytidine ee maskaxda ku dhex jira (oo hadhow u rogaya uridine). Bini'aadamka, Citicoline Sodium waa nafaqo muhiim u ah doorkeeda yaraynta cilladaha tuubbada neerfaha ee halista ah, cudurka beerka dufanka badan, iyo cuduro kale ayaa la diiwaangeliyey. CDP-choline Sodium waa mid ka mid ah saddexda maaddo ee ay ku jiraan fosforypatids-ka ee afka lagu kabi karo (labada kale waa alpha-GPC iyo fosfatidylcholine).

 

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) faa'iidooyinka

CDP-choline wuxuu kiciyaa biosynthesis of phospholipids-ka qaabdhismeedka xuubka neerfaha, wuxuu kordhiyaa dheef-shiid kiimikaadka maskaxda wuxuuna wax ka qabtaa heerarka neurotransmitters-ka kala duwan. Sidaa awgeed, waxaa si tijaabo ah loo caddeeyay in CDP-choline ay kordhiso heerarka noradrenaline iyo dopamine ee CNS.

Caawinaadkan waxaa loo adeegsadaa si looga hortago ama loo daweeyo dhibaatooyinka xasaasiga ah ee la xiriira waayeelka sababtoo ah xaqiiqda ah in labadaba ay labadiinaba qirayaan in ay yihiin kuwo neerfotin ah oo laga yaabo inay kor u qaadaan barashada. Inkastoo ay u muuqato in ay ka waxtar badan tahay fosfatidylcholine (PC) doorashadan, qayb ahaan sababtoo ah kordhinta PC kombiyuutarka ee maskaxda, awooddiisu waxay u eg tahay mid la mid ah tan Alpha-GPC.

 

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) isticmaalka

CDP-choline waxay leedahay adeegsiyo kale oo suurtagal ah oo laxiriira garashada. Waxaa badanaa loo isticmaalaa sidii loo xoojin lahaa xusuusta dhalinyarada, laakiin in kasta oo daraasado jireed qaarkood ay soo jeedinayaan in tani ay macquul tahay afka CDP-choline, ma jiraan daraasado bini aadam oo dhalinyarada xilligan la joogo. Hal daraasad ayaa xustay kororka feejignaanta leh qiyaasta hoose ee CDP-choline (oo loo baahan yahay in la soo koobo), iyo CDP-choline ayaa laga yaabaa inay door ku yeelato sidii xarun ka hortag u ah qabatinka ka hortagga kookeynta iyo (caddaynta hordhaca ah waxay soo jeedinaysaa) cuntada sidoo kale ..

 

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) Codsiga

Budada 'Citicoline Sodium' (CDP Choline Sodium) budada waa wakiil neuroprotective. Waxay ku shaqeysaa kor u qaadida isgaarsiinta gacanta, kicinta isku-darka SAMe, iyo kordhinta dheef-shiid kiimikaadka. Budada Citicoline Sodium (CDP Choline Sodium) budada waa si dabiici ah u dhaca nucleotide; dhexdhexaad ah dariiqa weyn ee lecitin biosynthesis. Neuroprotective. Waxaa loo isticmaalaa daaweynta istaroogga dhiig-baxa maskaxda iyo dhaawaca madaxa. Wax soo saarka Neuroprotective. Citicholine wuxuu ku muujiyaa waxyeelo ilaalin ah maskaxda maskaxda, dhaawaca maskaxda, iyo ciladaha xusuusta. Dhawaan ayaa muujisay waxtarka ka dhanka ah waallida markii la siiyay AchEIs (Acetylcholinesterase inhibitor). Waxay tilmaamaysaa Neuroprotective, waxqabadka acnticonvulsant iyo saameynta daawada ee qiyaasta 150mg / kg ee jiirka. Waxay muujisay difaac ka dhan ah cilladaha garashada cilladaha aluminium ee jiirka oo yareynaya heerka sare ee glutamate, oksidheer cadaadis iyo wax soo saar badan oo ah hippocampus.

 

Citicoline Sodium (CDP Choline Sodium)(33818-15-4) budo for sale

(Xagee laga iibsan karaa Citicoline Sodium (CDP Choline Sodium)(33818-15-4) budada jumlada)

Shirkaddayadu waxay ku raaxeysataa xiriirro waqti dheer leh macaamiisheena maxaa yeelay waxaan diiradda saareynaa adeegga macaamiisha iyo bixinta alaabada waa weyn. Haddii aad xiiseyneyso badeecadeena, waxaan la qabsaneynaa qaabaynta amarrada ku habboon baahiyahaaga gaarka ah iyo waqtigeenna dhakhsaha ah ee hoggaanka amarada dammaanad-qaadista waxaad kuheli doontaa cuntadeena waqtigeeda waqtigeeda. Waxaan sidoo kale diirada saareynaa adeegyada qiimeynta ku jira. Waxaan diyaar u nahay su'aalaha adeegga iyo macluumaadka si aan u taageerno meheraddaada.

Waxaan nahay xirfadle Citicoline Sodium (CDP Choline Sodium)(33818-15-4) iibiyaha budada muddo dhowr sano ah, waxaan ku siineynaa badeecado qiimo tartan leh, wax soo saarkeenuna waa kan ugu tayada sareeya waxaana maraya tijaabooyin adag oo madax banaan si loo hubiyo inay amaan u tahay isticmaalka adduunka.

 

tixraacyada

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[2] Jiang JJ, Xie YM, Zhang Y, Zhang YK, Wang ZM, Han B. [Astaamaha dawooyinka ee cirbadaha Shuhinening ee daaweynta cilmi baarista unugyada maskaxda ee ku saleysan diiwaangelinta]. Zhongguo Zhong Yao Za Zhi. 2016 Dec; 41 (24): 4516-4520. doi: 10.4268 / cjcmm20162407. Shiine. PubMed PMID: 28936832.

[3] Liu Y, Wang J, Xu C, Chen Y, Yang J, Liu D, Niu H, Jiang Y, Yang S, Ying H. Wax ku ool ah oo wax soo saar badan oo CDP-choline ah oo ay hogaamineyso barnaamijka deeqbixiyaasha ATP. Appl Microbiol Biotechnol. 2017 Feb; 101 (4): 1409-1417. doi: 10.1007 / s00253-016-7874-0. Epub 2016 Oct 13. PubMed PMID: 27738720.

[4] Giménez R, Raïch J, Aguilar J (Nofeembar 1991). "Isbeddelada ku dhaca maskaxda maskaxda ee loo yaqaan" dopamine striatum dopamine "iyo acetylcholine receptors oo ay keento daaweyn joogto ah oo loo yaqaan 'CDP-choline' oo lagu daweeyo jiirka jiirka ah". Joornaalka Ingiriiska ee Farmashiga. 104 (3): 575-8. doi: 1111 / j.1476-5381.1991.tb12471.x. PMC1908237PMID1839138.

[5] Tardner, P. (2020-08-30). "Isticmaalka 'citicoline' ee daaweynta hoos u dhaca garashada iyo garashada cillad la'aanta: Falanqaynta metaleed ee suugaanta dawooyinka • Joornaalka Caalamiga ah ee Sayniska Deegaanka & Teknolojiyada". Joornaalka Caalamiga ah ee Sayniska & Teknolojiyada Deegaanka. La soo celiyey 2020-08-31.